do you lose muscle on tirzepatide How Semaglutide and Affect Mass Tirzepatide‐induced body composition changes: Implications

empty stomach Pre-filled pen, no reconstitution needed Safety Comparison# Both agents share the GLP-1 agonist class side effect profile: nausea, vomiting, diarrhea, constipation, and abdominal pain, predominantly during dose escalation

Dhindsa S, et al

Knapen (86) also reported through follow-up studies that the pancreatic tumor risk in patients treated with GLP-1RA for a long period of time was not significantly different

Dehydration from gastrointestinal side effects may be compounded by reduced fluid intake, especially if patients experience nausea or reduced appetite, another common effect of tirzepatide

Translation: It may not be the weight loss alone that's to blame for your sagging